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NF-κB Signaling | NF-kappaB Pathway
NF-κB Signaling | NF-kappaB Pathway

PI3K inhibitors are finally coming of age | Nature Reviews Drug Discovery
PI3K inhibitors are finally coming of age | Nature Reviews Drug Discovery

Inhibition of the Nuclear Factor κB (NF-κB) Pathway by Tetracyclic Kaurene  Diterpenes in Macrophages - Journal of Biological Chemistry
Inhibition of the Nuclear Factor κB (NF-κB) Pathway by Tetracyclic Kaurene Diterpenes in Macrophages - Journal of Biological Chemistry

Inhibition of nuclear factor kappa B inducing kinase suppresses  inflammatory responses and the symptoms of chronic periodontitis in a mouse  model - ScienceDirect
Inhibition of nuclear factor kappa B inducing kinase suppresses inflammatory responses and the symptoms of chronic periodontitis in a mouse model - ScienceDirect

Defective Lymphotoxin-β Receptor-Induced NF-κB Transcriptional Activity in  NIK-Deficient Mice
Defective Lymphotoxin-β Receptor-Induced NF-κB Transcriptional Activity in NIK-Deficient Mice

NF-κB-Inducing Kinase Is Dispensable for Activation of NF-κB in  Inflammatory Settings but Essential for Lymphotoxin β Receptor Activation  of NF-κB in Primary Human Fibroblasts | The Journal of Immunology
NF-κB-Inducing Kinase Is Dispensable for Activation of NF-κB in Inflammatory Settings but Essential for Lymphotoxin β Receptor Activation of NF-κB in Primary Human Fibroblasts | The Journal of Immunology

A TNF‐p100 pathway subverts noncanonical NF‐κB signaling in inflamed  secondary lymphoid organs | The EMBO Journal
A TNF‐p100 pathway subverts noncanonical NF‐κB signaling in inflamed secondary lymphoid organs | The EMBO Journal

Identification of N-Phenyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine Derivatives  as Novel, Potent, and Selective NF-κB Inducing Kinase (NIK) Inhibitors for  the Treatment of Psoriasis | Journal of Medicinal Chemistry
Identification of N-Phenyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine Derivatives as Novel, Potent, and Selective NF-κB Inducing Kinase (NIK) Inhibitors for the Treatment of Psoriasis | Journal of Medicinal Chemistry

FEP+ calculations predict a stereochemical SAR switch for first-in-class  indoline NIK inhibitors for multiple myeloma | Future Drug Discovery
FEP+ calculations predict a stereochemical SAR switch for first-in-class indoline NIK inhibitors for multiple myeloma | Future Drug Discovery

A NIK-SIX signalling axis controls inflammation by targeted silencing of  non-canonical NF-κB. - Abstract - Europe PMC
A NIK-SIX signalling axis controls inflammation by targeted silencing of non-canonical NF-κB. - Abstract - Europe PMC

The NF-KB pathway and endocrine therapy resistance in breast cancer in:  Endocrine-Related Cancer Volume 26 Issue 6 (2019)
The NF-KB pathway and endocrine therapy resistance in breast cancer in: Endocrine-Related Cancer Volume 26 Issue 6 (2019)

Cancers | Free Full-Text | Targeting NF-κB Signaling for Multiple Myeloma |  HTML
Cancers | Free Full-Text | Targeting NF-κB Signaling for Multiple Myeloma | HTML

NIK promotes tissue destruction independently of the alternative NF-κB  pathway through TNFR1/RIP1-induced apoptosis | Cell Death & Differentiation
NIK promotes tissue destruction independently of the alternative NF-κB pathway through TNFR1/RIP1-induced apoptosis | Cell Death & Differentiation

Inhibition of nuclear factor kappa B inducing kinase suppresses  inflammatory responses and the symptoms of chronic periodontitis in a mouse  model - ScienceDirect
Inhibition of nuclear factor kappa B inducing kinase suppresses inflammatory responses and the symptoms of chronic periodontitis in a mouse model - ScienceDirect

GAPDH Overexpression in the T Cell Lineage Promotes Angioimmunoblastic T  Cell Lymphoma through an NF-κB-Dependent Mechanism - ScienceDirect
GAPDH Overexpression in the T Cell Lineage Promotes Angioimmunoblastic T Cell Lymphoma through an NF-κB-Dependent Mechanism - ScienceDirect

Structure of the Nuclear Factor κB-inducing Kinase (NIK) Kinase Domain  Reveals a Constitutively Active Conformation - Journal of Biological  Chemistry
Structure of the Nuclear Factor κB-inducing Kinase (NIK) Kinase Domain Reveals a Constitutively Active Conformation - Journal of Biological Chemistry

Essential Role of NF-κB-Inducing Kinase in T Cell Activation Through the  TCR/CD3 Pathway | The Journal of Immunology
Essential Role of NF-κB-Inducing Kinase in T Cell Activation Through the TCR/CD3 Pathway | The Journal of Immunology

Inhibition of nuclear factor kappa B inducing kinase suppresses  inflammatory responses and the symptoms of chronic periodontitis in a mouse  model - ScienceDirect
Inhibition of nuclear factor kappa B inducing kinase suppresses inflammatory responses and the symptoms of chronic periodontitis in a mouse model - ScienceDirect

Inhibition of nuclear factor kappa B inducing kinase suppresses  inflammatory responses and the symptoms of chronic periodontitis in a mouse  model - ScienceDirect
Inhibition of nuclear factor kappa B inducing kinase suppresses inflammatory responses and the symptoms of chronic periodontitis in a mouse model - ScienceDirect

Defective Lymphotoxin-β Receptor-Induced NF-κB Transcriptional Activity in  NIK-Deficient Mice
Defective Lymphotoxin-β Receptor-Induced NF-κB Transcriptional Activity in NIK-Deficient Mice

NF-κB inducing kinase is a therapeutic target for systemic lupus  erythematosus. - Abstract - Europe PMC
NF-κB inducing kinase is a therapeutic target for systemic lupus erythematosus. - Abstract - Europe PMC

IJMS | Free Full-Text | Small Molecule NF-κB Pathway Inhibitors in Clinic |  HTML
IJMS | Free Full-Text | Small Molecule NF-κB Pathway Inhibitors in Clinic | HTML

A Kinase Assay for Measuring the Activity of the NIK-IKK1 Complex Induced  via the Noncanonical NF-κB Pathway | SpringerLink
A Kinase Assay for Measuring the Activity of the NIK-IKK1 Complex Induced via the Noncanonical NF-κB Pathway | SpringerLink

XT2 | NIK inhibitor | Glixxlabs.com High Quality Supplier
XT2 | NIK inhibitor | Glixxlabs.com High Quality Supplier

Structure-Based Design of Tricyclic NF-κB Inducing Kinase (NIK) Inhibitors  That Have High Selectivity over Phosphoinositide-3-kinase (PI3K) | Journal  of Medicinal Chemistry
Structure-Based Design of Tricyclic NF-κB Inducing Kinase (NIK) Inhibitors That Have High Selectivity over Phosphoinositide-3-kinase (PI3K) | Journal of Medicinal Chemistry

6MYN: Crystal structure of murine NF-kappaB inducing kinase (NIK) bound to  inhibitor R7
6MYN: Crystal structure of murine NF-kappaB inducing kinase (NIK) bound to inhibitor R7